When to use SODERMIX®
Eczema is characterized by erythema, pruritus, vesiculation, and, in more chronic forms, scaly desquamation. Contact eczema may be due to chemically induced irritation or allergic sensitization.
In the working population of Western countries, contact eczema (both irritant and allergic) accounts for 85-90% of all occupational skin disease. Hand eczema has been estimated to affect 2-6.5% of all populations in Western countries.
The memory T cells that mediate allergic contact eczema are of the Th1 subtype, characterized by the production of interleukin 2 and interferon gamma, two potent cytokines. Tissues are activated to release cytokines (including interferon gamma) that attract other cells and activate vascular responses, resulting in the characteristic inflammation of contact eczema.
The causal agent should be identified by epi-cutaneous patch tests. Contact allergy can be induced by a huge range of substances encountered daily.
The patient should then be advised to avoid the causal agent.
Hence, by reducing the synthesis and secretion of cytokines and chemokines, Superoxide Dismutase (SOD) contained in SODERMIX® permits to: